Hotels in La Mesa (California, USA)

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462 hotels in La Mesa

    Heritage Inn La Mesa

    2 Stars

    Outdoor swimming pool and hot tub, Budget-friendly roadside base

    See prices from 13 sites
    from  $84

    Best Western Plus La Mesa San Diego

    3 Stars

    Outdoor pool and whirlpool, Spacious family-friendly suites

    See prices from 14 sites
    from  $160

  3. Holiday Inn Express La Mesa Near Sdsu By Ihg

    3 Stars

    Heated outdoor swimming pool, Modernized San Diego retreat

    See prices from 12 sites
    from  $180

  4. Motel 6 La Mesa, CA

    2 Stars

    Recently renovated guest rooms, Pet-friendly accommodations

    See prices from 11 sites
    from  $123

  5. Motel 6 La Mesa, CA - San Diego

    2 Stars

    Recently renovated rooms, Proximity to San Diego Trolley Green Line

    See prices from 12 sites
    from  $124

  6. Zen Retreat

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  7. Lake Murray 3BR Retreat with AC and Skylight

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  8. Luxurious Estate Home-sumptuous Views - Resort Like!

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  9. Wow! San Diego Vacation Home Rental, Family/bus Near Attractions Ocean View Pool

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  10. New, Charming 1-bedroom Home In Fletcher Hills, La Mesa. Centrally Located

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  11. Serenity - Amazing Views & Modern Charm

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  12. Entire Private Home with 4 Bedrooms 3 Bath, King Bed, Large Yard & Prime Area, Ranch Style, Available Now

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  13. Private Studio, Parking, Kitchen, 15 Mins to SD

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  14. Exotic Home Rogers By Sdstay

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  15. Walk to La Mesa Village: Apt w/ Private Patio

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  16. La Mesa Family Retreat - 20 Minutes To Beaches & More!

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  17. Serenity Garden Studio

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  18. Quaint La Mesa Townhome, Pet Friendly with Fee!

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  19. Stunning Brand New Top Of Mtn 2br Zen Retreat

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  20. Sunny San Diego Yellow Cottage Home, Beaches, Sea World, San Diego Zoo, Leisure

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  21. Poolside Oasis! New Saltwater Pool, Spa And Firepit

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  22. San Diego Luxury Oasis

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  23. Luxury 5br 3 5ba w Pool & Hot Tub

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  24. The Hillside Haven Your Family Adventure Awaits

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  25. Hidden King Suite with Garden Parking - 4 Guest

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  26. An Elegant, Fully Furnished Rental In Casa De Oro-mount Helix

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  27. The Helix House - Pool & Mountain Views

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  28. The Hidden Treasure Estate

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  29. Enjoy Stylish Heaven In La Mesa Steps To Everything, Near Ssu

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  30. California Dreamin Resort-Style Pool House

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  31. Stylish Studio With Wifi And Ac In Peaceful San Diego

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  32. The Sky Lounge

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  33. Your Own Suburban Oasis!

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  34. Echo by Coast to Cactus - Family-Friendly Home

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  35. Avoyer One Bedroom Guesthouse - La Mesa

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The prices and availability we receive from booking sites change constantly. This means you may not always find the exact same offer you saw on trivago when you land on the booking site.

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Popular hotel categories in La Mesa

When to book a hotel in La Mesa

  • Cheapest month: December
    $264 per night
  • Yearly typical price
    $323 per night
  • Peak month: May
    $389 per night

Frequently Asked Questions about La Mesa

  • When is the cheapest time to book a hotel in La Mesa?

    December is usually the cheapest month to book a hotel in La Mesa, with typical prices around $264 per night based on 2,195 price comparisons.

  • When are hotel prices highest in La Mesa?

    Hotel prices in La Mesa are usually highest during May, with typical prices around $389 per night.

  • How much does a hotel in La Mesa cost per night?

    Hotel prices in La Mesa usually range from $216 per night to $450 per night, with typical prices around $323 per night.

  • How do hotel prices in La Mesa change throughout the year?

    Hotel prices in La Mesa are typically lowest in December at around $264 per night, rising to around $389 per night in May.

  • October

    2026

    $305
    $213 — $403

  • November

    2026

    $280
    $213 — $401

  • December

    2026

    $264
    $216 — $363

  • January

    2027

    $328
    $278 — $425

  • February

    2027

    $322
    $252 — $435

  • March

    2027

    $355
    $305 — $478

  • April

    2027

    $324
    $290 — $421

  • May

    2027

    $389
    $341 — $450

  • June

    2027

    $289
    $223 — $390

  • July

    2027

    $327
    $252 — $483

  • August

    2027

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  • September

    2027

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Frequently Asked Questions about La Mesa

Hotels in La Mesa

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