Hotels in South San Francisco (California, USA)

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164 hotels in South San Francisco

  1. Comfort Inn & Suites San Francisco Airport North

    3 Stars
    Walkable dining in South San Francisco
    See prices from 14 sites
    from$90

  2. Park Pointe Hotel

    2 Stars
    Access to garden and gym
    See prices from 11 sites
    from$75

  3. Holiday Inn Express San Francisco-airport North By Ihg

    3 Stars
    On-Site Fitness and Whirlpool
    See prices from 15 sites
    from$108

  4. Embassy Suites by Hilton San Francisco Airport Oyster Point

    3 Stars
    Heated Indoor Pool and Gym
    See prices from 13 sites
    from$197

  5. Sonesta Select San Francisco Airport Oyster Point Waterfront

    3 Stars
    Scenic Bay Trail Access Point
    See prices from 14 sites
    from$141

  6. Best Western Plus Grosvenor Airport Hotel

    3 Stars
    Dine at The Brass Elephant
    See prices from 15 sites
    from$141

  7. Hilton Garden Inn San Francisco Airport North

    3 Stars
    Proximity to SFO and Biotech
    See prices from 12 sites
    from$119

  8. La Quinta Inn & Suites by Wyndham San Francisco Airport N

    3 Stars
    Nearby dining options within walking
    See prices from 13 sites
    from$139

  9. AC Hotel San Francisco Airport/Oyster Point Waterfront

    4 Stars
    Proximity to SFO Airport
    See prices from 14 sites
    from$186

  10. Hotel Focus SFO

    3 Stars
    Responsive Front Desk Support Team
    See prices from 13 sites
    from$98

  11. Hotel Nova SFO by FairBridge

    3 Stars
    Proximity to San Francisco Airport
    See prices from 11 sites
    from$150

  12. Home2 Suites by Hilton San Francisco Airport North

    3 Stars
    Maintain routines at Spin2 Cycle
    See prices from 13 sites
    from$163

  13. Hampton Inn San Francisco Airport

    3 Stars
    Proximity to San Francisco Airport
    See prices from 14 sites
    from$149

  14. DoubleTree by Hilton San Francisco South Airport Blvd

    4 Stars
    Dine at The Landing Restaurant
    See prices from 12 sites
    from$154

  15. Inn By The SFO

    2 Stars
    Convenient Highway 101 Access
    See prices from 4 sites
    from$142

  16. Larkspur Landing Extended Stay Suites South San Francisco

    3 Stars
    On-site fitness room access
    See prices from 14 sites
    from$123

  17. Fairfield by Marriott Inn & Suites San Francisco Airport Oyster Point Area

    3 Stars
    Convenient access to SFO Airport
    See prices from 14 sites
    from$155

  18. Four Points by Sheraton Hotel & Suites San Francisco Airport

    3 Stars
    Partnered Uber transportation services
    See prices from 13 sites
    from$139

  19. Days Inn by Wyndham San Francisco S/Oyster Point Airport

    2 Stars
    Recently renovated modern guest rooms
    See prices from 15 sites
    from$123

  20. Travelers Inn

    2 Stars
    Proximity to public transit options
    See prices from 11 sites
    from$139

  21. Rodeway Inn South San Francisco Airport

    2 Stars
    Reach SFO Airport within minutes
    See prices from 14 sites
    from$84

  22. Royal Inn

    2 Stars
    Proximity to San Francisco Airport
    See prices from 11 sites
    from$123

  23. Airport Inn

    2 Stars
    Proximity To San Francisco Airport
    See prices from 13 sites
    from$140

  24. All Seasons Lodge

    2 Stars
    Access San Francisco International Airport
    See prices from 3 sites
    from$148

  25. Deluxe Inn

    1 Stars
    Walk to South San Francisco Museum
    See prices from 13 sites
    from$256

  26. Americana Inn Motel

    2 Stars
    Select rooms with massage chairs
    See prices from 11 sites
    from$172

  27. Citigarden

    Select dates to see exact prices

  28. Travelodge by Wyndham San Francisco Airport North

    2 Stars
    On-site 24-Hour IHOP Dining
    See prices from 13 sites
    from$69

  29. New Remodeled 3-Bedroom South San Francisco Home

    Select dates to see exact prices

  30. Modern, Chic, 3Br/2Ba Flat, Nice Out Door Patio Area, Light Breakfast Included.

    Select dates to see exact prices

  31. Pleasant Stay, Convenient Location! 2 Convenient Units, Pets Allowed

    Select dates to see exact prices

  32. SFO Airport/S San Francisco Sweet Home

    Select dates to see exact prices

  33. Americas Best Value Inn & Suites-San Francisco Airport North

    2 Stars
    Select dates to see exact prices

  34. Hotel Inn at Oyster Point

    3 Stars
    Select dates to see exact prices

  35. Inviting Studio Suite W/ Kitchen In Sf - Work Desk, Living Space, Pets Welcome

    Select dates to see exact prices

The prices and availability we receive from booking sites change constantly. This means you may not always find the exact same offer you saw on trivago when you land on the booking site.

Other stays in South San Francisco

Popular hotel categories in South San Francisco

When to book a hotel in South San Francisco

  • Cheapest month: July
    $165 per night
  • Yearly typical price
    $248 per night
  • Peak month: October
    $381 per night

Frequently Asked Questions about South San Francisco

  • When is the cheapest time to book a hotel in South San Francisco?

    July is usually the cheapest month to book a hotel in South San Francisco, with typical prices around $165 per night based on 36 price comparisons.

  • When are hotel prices highest in South San Francisco?

    Hotel prices in South San Francisco are usually highest during October, with typical prices around $381 per night.

  • How much does a hotel in South San Francisco cost per night?

    Hotel prices in South San Francisco usually range from $111 per night to $1,156 per night, with typical prices around $248 per night.

  • How do hotel prices in South San Francisco change throughout the year?

    Hotel prices in South San Francisco are typically lowest in July at around $165 per night, rising to around $381 per night in October.

  • November

    2026

    $211
    $154 — $419

  • December

    2026

    $206
    $153 — $320

  • January

    2027

    $229
    $158 — $488

  • February

    2027

    $246
    $171 — $358

  • March

    2027

    $326
    $201 — $491

  • April

    2027

    $252
    $178 — $385

  • May

    2027

    $250
    $170 — $296

  • June

    2027

    $313
    $202 — $436

  • July

    2027

    $165
    $111 — $190

  • August

    2027

    $186
    $135 — $217

  • September

    2027

    $294
    $205 — $435

  • October

    2027

    $381
    $197 — $1,156

Frequently Asked Questions about South San Francisco

Hotels in South San Francisco

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