Hotels in Murphysboro (Illinois, USA)

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63 hotels in Murphysboro

  1. Holiday Inn Express & Suites Murphysboro - Carbondale By Ihg

    3 Stars
    Indoor Heated Pool and Gym
    See prices from 10 sites
    from$128

  2. Lakefront, Pet-friendly 1BR w/ Porch & Fire Pit

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  3. Lakefront, Pet-Friendly Studio Cabin with Porch

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  4. Mudline Lodging your premier Cabin, RV & Campsite Rental in Southern Illinois!

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  5. Americas Best Value Inn Murphysboro - Carbondale

    4 Stars
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  6. Murphysboro Retreat With Deck Near Kinkaid Lake!

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  7. Blue Line Resort Cabin #3

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  8. Blue Line Resort Cabin #2

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  9. Cozy cabin close to Kinkaid Lake Murphysboro

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  10. Private Ridge Lodge 4 Suites Sauna

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  11. Spacious Shawnee Forest Hideaway! Hilltop Estate

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  12. Stunning 8-bedroom barndo on a 24-acre farm with pond, located on wine trail

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  13. Stay N Play Cabin Close to Kinkaid Lake

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  14. Closest Stay to the Paul Ice Boat Ramp - Sleeps 8

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  15. Murphysboro BnB

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  16. 2BR Luxury Retreat, Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit

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  17. Cozy 2-bedroom log cabin style house in quaint Murphysboro overlooking a lake.

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  18. 3-bedroom Home nRoyal Haven Vacation Destination

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  19. Lois' HideoutnnComfy 1 bedroom camper within 7 minutes of Kinkaid Lake.

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  20. Kinkaid Kamper With Ac In Oraville - 2 Bedrooms For A Cozy Stay

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  21. Fully Custom Modern Four Bedroom Home On 13 Acres With A Stocked Pond.

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  22. Kinkaid Lake cabin rental located next to Marina

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  23. Charming 3-bedroom House In Tranquil Oraville Minutes From Kinkaid Lake.

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  24. Your Small Town Getaway-Alex Lane Fairytale Stay

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  25. Minutes from Lake |Fire Pit | Like-New 3BR Retreat

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  26. Beautiful Cabin Experience

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  27. Our Murphy Home in Murphysboro IL

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  28. Home2 Suites by Hilton Carbondale

    3 Stars
    Convenient access to Amtrak station
    See prices from 12 sites
    from$140

  29. Super 8 by Wyndham Carbondale

    2 Stars
    Access Southern Illinois University easily
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  30. Hampton Inn Carbondale

    3 Stars
    Indoor Pool and Fitness Center
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  31. Walker's Bluff Casino Resort

    Indoor and outdoor pool access
    See prices from 9 sites
    from$201

  32. Holiday Inn Express & Suites Carbondale - University Area by IHG

    3 Stars
    Proximity to Southern Illinois University
    See prices from 11 sites
    from$145

  33. Best Western Saluki Inn

    3 Stars
    Convenient Location Near SIU Campus
    See prices from 13 sites
    from$120

  34. Days Inn & Suites Carbondale

    3 Stars
    On-site fitness and business centers
    See prices from 11 sites
    from$98

  35. Super 8 Motel - Carbondale

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The prices and availability we receive from booking sites change constantly. This means you may not always find the exact same offer you saw on trivago when you land on the booking site.

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Popular hotel categories in Murphysboro

When to book a hotel in Murphysboro

  • Cheapest month: December
    $178 per night
  • Yearly typical price
    $194 per night
  • Peak month: April
    $213 per night

Frequently Asked Questions about Murphysboro

  • When is the cheapest time to book a hotel in Murphysboro?

    December is usually the cheapest month to book a hotel in Murphysboro, with typical prices around $178 per night based on 649 price comparisons.

  • When are hotel prices highest in Murphysboro?

    Hotel prices in Murphysboro are usually highest during April, with typical prices around $213 per night.

  • How much does a hotel in Murphysboro cost per night?

    Hotel prices in Murphysboro usually range from $146 per night to $267 per night, with typical prices around $194 per night.

  • How do hotel prices in Murphysboro change throughout the year?

    Hotel prices in Murphysboro are typically lowest in December at around $178 per night, rising to around $213 per night in April.

  • November

    2026

    $195
    $161 — $294

  • December

    2026

    $178
    $146 — $224

  • January

    2027

    $186
    $154 — $237

  • February

    2027

    $191
    $176 — $212

  • March

    2027

    $192
    $178 — $213

  • April

    2027

    $213
    $177 — $267

  • May

    2027

    $195
    $181 — $216

  • June

    2027

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  • July

    2027

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  • August

    2027

    $195
    $179 — $210

  • September

    2027

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  • October

    2027

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Frequently Asked Questions about Murphysboro

Hotels in Murphysboro

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